Dr. Mark Njogu Kimani Publications

Publications with peer review process:

2024

1. Mwanza, S.S.; Mudalungu, C.M.; Kimani, N.M.; Mokaya, H.O.; Ochieng, B.O.; Juma, S.; Tanga, C.M. (2024). Nutritional and antioxidant properties of two species of edible scarab beetles (Cetonia aurata and Oryctes rhinoceros). Journal of Insects as Food and Feed. https://doi.org/10.1163/23524588-00001009
2. Kibet, S.; Mudalungu, C.M.; Kimani, N.M.; Makwatta, J.O.; Kabii, J.; Sevgan, S.; Kelemu, S.; Tanga, C.M. (2024). Unearthing Lactococcus lactis and Scheffersomyeces Symbionts from Edible Wood-Boring Beetle Larvae as a Bio-Resource for Industrial Applications. BMC Microbiology. 24, 282, doi:10.1186/s12866-024-03428-9.
3. Obende, S.O.; Ochieng, C.O.; Shikanga, E.A.; Cruz, J.N.; Santos,C.B.D.; Kimani, N.M. (2024). Croton's therapeutic promise: A review of its phytochemistry and critical computational ADME/Tox analysis. South African Journal of Botany.171, 648-672, https://doi.org/10.1016/j.sajb.2024.06.031.
4. Bastos, R.S.; de Aguiar, C.P.O.; Cruz, J.N.; Ramos, R.S.; Kimani, N.M.; de Souza, J.S.N.; Chaves, M.H.; de Freitas, H.F.; Pita, S.S.R.; Santos, C.B.R.d. (2024). Rational Approach toward COVID-19′s Main Protease Inhibitors: A Hierarchical Biochemoinformatics Analysis. International Journal of Molecular Sciences.25, 6715. https://doi.org/10.3390/ijms25126715
5. Kibet S.; Mudalungu C.M.; Ochieng B.O.; Mokaya H.O.; Kimani N.M.; Tanga C.M. (2024). Nutritional composition of edible wood borer beetle larvae in Kenya. PLoS One. Jun 6;19(6):e0304944. doi: 10.1371/journal.pone.0304944. 
6. Chepkemoi, J., Pfütze, S., Kimani, N.M., Matasyoh, J., Stadler, M. (2024). Comparison of the Secondary Metabolism of the Basidiomycetes Armillaria mellea and Desarmillaria ectypa. Chemistry & Biodiversity, e202400933.  https://doi.org/10.1002/cbdv.202400933
7. Kibet, S.; Kimani, N.M. *; Mwanza, S.S.; Mudalungu, C.M.; Santos, C.B.R.; Tanga, C.M. (2024). Unveiling the Potential of Ent-Kaurane Diterpenoids: Multifaceted Natural Products for Drug Discovery. Pharmaceuticals 2024, Vol. 17, Page 510 2024, 17, 510, doi:10.3390/PH17040510.http://dx.doi.org/10.3390/ph17040510
8. Santos, C. B., Cruz, J. N., Federico, L. B., Mali, S. N., Kimani, N. M., Lobato, C. C., Silva, R. C., Bittencourt, J. A., Bastos, R. S., Da Costa, R. A., & Da Silva, C. H. (2024). Structure-based drug design for protein arginine deiminase Type IV (PAD4) receptor: Chemoinformatics approach. Chemical Physics Impact, 8, 100464. https://doi.org/10.1016/j.chphi.2024.100464

2023

1. Wekesa, E. N., Kimani, N. M.*, Kituyi, S. N., Omosa, L. K., & Santos, C. B. (2023). Therapeutic Potential of the Genus Zanthoxylum Phytochemicals: A Theoretical ADME/Tox Analysis. South African journal of botany, 162, 129-141.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:qxL8FJ1GzNcC
2. Nyariki, J. N. *, Kimani, N. M., Kibet, P. S., Kinuthia, G. K., Isaac. A. O. (2023). Coenzyme Q10 exhibits anti-inflammatory and immune-modulatory thereby decelerating the occurrence of experimental cerebral malaria. Molecular and Biochemical Parasitology, 111579. https://doi.org/10.1016/j.molbiopara.2023.111579
3. Bastos, R. S., de Lima, L R., Neto, M. F. de A., Maryam, Yousaf, N., Cruz, J. N., Campos, J. M., Kimani, N. M., Ramos, R. S., Santos, C. B. R.*(2023): Design and Identification of Inhibitors for the Spike-ACE2 Target of SARS-COV-2. International Journal of Molecular Sciences. 24(10):8814. https://doi.org/10.3390/ijms24108814
4. Ojuka, P., Kimani, N. M.*, Apollo, S., Nyariki, J., Ramos, R. S., Santos, C. B. R. (2023): Phytochemistry of the genus Vepris plants: a review and in silico analysis of their ADMET properties. South African Journal of Botany. 157(2023):106-114
5. Kimani, N. M.*, Ochieng, C. O., Ogutu, M. K., Yamo, K. O., Onyango, J. O. (2023): Inhibition kinetics and theoretical studies on Zanthoxylum chalybeum dual inhibitors of α-glucosidase and α-amylase. Journal of Xenobiotics. 13(1):102-120. https://doi.org/10.3390/jox13010009
6. Silva, L. B., Ferreira, E. F. B., Maryam, Espejo-Román, J. M., Costa, G. V., Cruz, J. V., Kimani, N. M., Costa, J. S., Bittencourt, J. A. H. M., Cruz, J. N., Campos, J. M., Santos, C. B. R. * (2023): Galantamine Based Novel Acetylcholinesterase Enzyme Inhibitors: A Molecular Modeling Design Approach. Molecules.  28(3): 1035. https://doi.org/10.3390/molecules28031035

2022

1. Cruz, J. V., Campos, J. M., Kimani, N. M., Giuliatti, S., Santos, C. B. R.* (2022): The role of celecoxib as a potential inhibitor in the treatment of inflammatory diseases - a review. Current Medicinal Chemistry. 29(17): 3028-3049. do1: 2174/0929867328666210217153609

2021 - 2017

1. Rai C. Silva, Humberto F. Freitas, Joaquín M. Campos, Njogu M. Kimani, Carlos H. T. P. Silva, Rosivaldo S. Borges, Samuel S. R. Pita and Cleydson B. R. Santos. Natural Products-Based Drug Design against SARS-CoV-2 Mpro 3Clpro. International Journal of Molecular Sciences 2021.  DOI: 10.3390/ijms222111739.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:kNdYIx-mwKoC
2. Elenilze F.B. Ferreira, Luciane B. Silva, Josiane V. Cruz, Pedro H.F. Araújo, Njogu M. Kimani, Franco H.A. Leite, Joaquín M. Campos, and Cleydson B.R. Santos. An Overview of the α4β1 Integrin and the Potential Therapeutic Role of its Antagonists. Current Medicinal Chemistry 2021 (28). DOI: 10.2174/0929867328666210217153609.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:MXK_kJrjxJIC
3. Josiane Viana Cruz, Joaquín María Campos Rosa, Njogu Mark Kimani, Silvana Giuliatti, Cleydson Breno Rodrigues dos Santos. The role of celecoxib as a potential inhibitor in the treatment of inflammatory diseases - a review. Current Medicinal Chemistry 2021 (28). DOI: 10.2174/0929867328666210217153609.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:3fE2CSJIrl8C
4. Josiane V. Cruz, Silvana Giuliatti, Levy B. Alves, Raí C. Silva, Elenilze F. B. Ferreira, Njogu M. Kimani, Carlos H. T. P. Silva, João S. N. de Souza, José M. Espejo-Romá, and Cleydson B. R. Santos.Identification of novel potential cyclooxygenase-2 inhibitors using ligand- and structure-based virtual screening approaches. Journal of Biomolecular Structure and Dynamics 2021. DOI: 10.1080/07391102.2020.1871413.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:8k81kl-MbHgC
   
5. Njogu M. Kimani, Solveig Backhaus, Josphat C. Matasyoh, Marcel Kaiser, Fabian Herrmann, Thomas J. Schmidt, Klaus Langer. Preparation of sesquiterpene lactone-loaded PLA nanoparticles and evaluation of their antitrypanosomal activity. Molecules 24(11), 2110 (2019); doi: 10.3390/molecules24112110.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:roLk4NBRz8UC
6. Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Mauro S. Nogueira, Gustavo H. G. Trossini, Thomas J. Schmidt. Complementary quantitative structure-activity relationship models for the antitrypanosomal activity of sesquiterpene lactones. International. Journal of Molecular Sciences 19, 3721 (2018), doi:10.3390/ijms19123721.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:_FxGoFyzp5QC
7. Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Thomas J. Schmidt.  Sesquiterpene lactones from Vernonia cinerascens Sch. Bip. and their in vitro antitrypanosomal activity. Molecules 23(2), 248 (2018); doi: 10.3390/molecules23020248.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:eQOLeE2rZwMC
8. Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Thomas J. Schmidt. Antiprotozoal sesquiterpene lactones and other constituents from Tarchonanthus camphoratus and Schkuhria pinnata. Journal of Natural Products, 81(1), 124-130(2018); doi:10.1021/acs.jnatprod.7b00747.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:W7OEmFMy1HYC
9. Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Thomas J. Schmidt. Anti-Trypanosomatid Elemanolide Sesquiterpene Lactones from Vernonia lasiopus O. Hoffm. Molecules 22(4), 597 (2017); doi: 10.3390/molecules22040597.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:UeHWp8X0CEIC

2015-2014

1. Amos Kanyora, Thomas Kinyanjui, Samuel Kariuki, Mark Njogu.  Fluoride removal capacity of regenerated bone char in treatment of drinking water. Asian Journal of Natural and Applied Sciences (AJSC) 4(1), 30-36 (2015).https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:d1gkVwhDpl0C
2. Mark Njogu, Josphat C. Matasyoh,  Alfred C. Kibor. Rapanea melanophloeos leaf extracts against Schistosoma mansoni miracidia. Research 2, 1303 (2015); doi: 10.13070/rs.en.2.1303.https:////dx.doi.org/10.13070/rs.en.2.1303
3. Mark Njogu, Josphat C. Matasyoh,  Alfred C. Kibor. Antihelmintic activity of Teclea nobilis methanol, ethyl acetate and hexane extracts against Schistosoma mansoni. Research 1, 1234 (2014); doi: 10.13070/rs.en.1.1234.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:2osOgNQ5qMEC
4. Mark Njogu, Josphat C. Matasyoh, Alfred C. Kibor. Antischistosomal benzoic acid derivatives from Rapanea melanophloeos against the Schistosoma mansoni miracidia. Research 1, 1171 (2014); 10.13070/rs.en.1.1171.https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:9yKSN-GCB0IC
5. Mark Njogu, Josphat C. Matasyoh, Alfred C. Kibor. Chemical composition and antihelmintic activity of Teclea nobilis essential oil against Schistosoma mansoni miracidia. Journal of Pharmaceutical and Biomedical Sciences 4(10), 880-886 (2014).https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:zYLM7Y9cAGgC
6. Mark Njogu, Josphat C. Matasyoh,  Alfred C. Kibor. Isolation of four furoquinoline alkaloids from Teclea nobilis and their activity against Schistosoma mansoni miracidia. Journal of Biomedical and Pharmaceutical Research 3(4), 87-93 (2014).https://scholar.google.com/citations?view_op=view_citation&hl=en&user=AFLVwt4AAAAJ&citation_for_view=AFLVwt4AAAAJ:YsMSGLbcyi4C

2022 - Book chapter with peer review

1. Evans, R. T., Apollo, S.*, Murithi, L. G., Kimani, N. M. (2022): Application of Bio-Based and Inorganic Composite Materials to Remove Heavy Metals from Textile Effluent. In: Muthu, S. S., Khadir, A. (eds) Textile Wastewater Treatment. Sustainable Textiles: Production, Processing, Manufacturing & Chemistry. Springer, Singapore. https://doi.org/10.1007/978-981-19-2852-9_10

Presentation of Papers at Academic and Professional Conferences

1.    Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Mauro S. Nogueira, Gustavo H.G. Trossini, Thomas J. Schmidt. Sesquiterpene lactones: quantitative structure-antitrypanosomal activity relationships (QSAR). In: 5th Young Researcher Meeting, 2019, Munster, Germany (oral presentation)
2.    Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Solveig Backhaus, Fabian Herrmann, Klaus Langer, Thomas J. Schmidt. Encapsulation of sesquiterpene lactones with antitrypanosomal activity into PLA nanoparticles. In: 5th Young Researcher Meeting, 2019, Munster, Germany (poster presentation)
3.    Njogu M. Kimani, Josphat C. Matasyoh, Solveig Backhaus, Klaus Langer, Thomas J. Schmidt. PLA nanoparticles loaded with antitrypanosomal sesquiterpene lactones. In: 8th NRW Nano Conference, 2018, Dortmund, Germany (poster presentation)
4.    Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Gustavo H.G. Trossini, Thomas J. Schmidt. An extended study on quantitative structure-antitrypanosomal activity relationships of sesquiterpene lactones. In: 4th International Electronic Conference on Medicinal Chemistry, 2018. (poster presentation)
5.    Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Gustavo H.G. Trossini, Thomas J. Schmidt. An extended study on quantitative structure-antitrypanosomal activity relationships of sesquiterpene lactones. In: 3rd WWU-USP summer school, 2018, Sao Paulo, Brazil (poster and oral presentation)
6.    Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Thomas J. Schmidt. Antitrypanosomal sesquiterpene lactones from Vernonia cinerascens. In: Phytotherapiekongress, 2017, Münster, Germany, Zeitschrift für Phytotherapie 38, DOI: 10.1055/s-0037-1607128
7.    Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Thomas J. Schmidt. Antiprotozoal sesquiterpene lactones from Schkuhria pinnata, Tarchonanthus camphoratus and Vernonia lasiopus. In: 2nd WWU-USP summer school 2017, Ribeirão Preto, Brazil. Book of Abstracts, ST16, p. 16.
8.    Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Thomas J. Schmidt. Antiprotozoal sesquiterpene lactones and other constituents from Schkuhria pinnata, Tarchonanthus camphoratus and Vernonia lasiopus. In: 65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), 2017, Basel, Switzerland. Planta medica, GA 2017-Book of Abstracts, DOI: 10.1055/s-0037-1608192.
9.    Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Thomas J. Schmidt. IV Anti-trypanosomal elemanolide sesquiterpene lactones from Vernonia lasiopus O. Hoffm. In: IV Symposium of Tropical Health/COST Action CM 1307 (WG3 and WG4) Joint meeting, 2017, Pamplona, Spain. Book of Abstract, p. 24.
10.    Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Thomas J. Schmidt. Antiprotozoal natural products from selected Kenyan plants of the family Asteraceae. In: The 17th NAPRECA Symposium on Natural Products, 2017, Addis Ababa, Ethiopia. Book of Abstract, P. 15.
11.    Njogu M. Kimani, Josphat C. Matasyoh, Marcel Kaiser, Reto Brun, Thomas J. Schmidt. Anti-trypanosomatid sesquiterpene lactones from selected Kenyan plants. In: DAAD scholarship holders meeting, 2016, Duesseldorf, Germany. Book of Abstract, p. 20
12.    Njogu M. Kimani, Josphat C. Matasyoh, Alfred C. Kibor. Rapanea melanophloeos and Teclea nobilis antihelmintic secondary metabolites. In: The 8th International KCS conference, 2015, University of Nairobi, Nairobi, Kenya. Book of Abstract, p. 32.
13.    Njogu M. Kimani, Josphat C. Matasyoh, Alfred C. Kibor. Rapanea melanophloeos and Teclea nobilis antihelmintic secondary metabolites. In: The 9th Egerton University International Conference, 2015, Egerton University, Njoro, Kenya. Book of Abstract, p. 55.
14.    Njogu M. Kimani, Josphat C. Matasyoh, Alfred C. Kibor. Antischistosomal benzoic acid derivative from Rapanea melanoploeos against the Schistosoma mansoni miracidia. In: 2nd International Conference, 2014, Laikipia University, Laikipia, Kenya. Book of Abstract, p. 68.
15.    Njogu M. Kimani, Josphat C. Matasyoh, Alfred C. Kibor. Miracidicidal activity of furoquinoline alkaloids from Teclea nobilis against the Schistosoma mansoni miracidia. In: The 8th Egerton University International Conference, 2014, Egerton University, Njoro, Kenya. Book of Abstract, p. 110.